Journal: Nature Communications

Article Title: Synthesis of macrocyclic nucleoside antibacterials and their interactions with MraY

doi: 10.1038/s41467-022-35227-z

Figure Lengend Snippet: Antibacterial activity of SPM-3 against drug-resistant and clinically isolated strains

Article Snippet: E. faecalis (VRE) , ATCC 51299 , 1 , 128 , 1 , 1.

Techniques: Activity Assay, Isolation

Journal: ACS Medicinal Chemistry Letters

Article Title: Bromomethylthioindole Inspired Carbazole Hybrids as Promising Class of Anti-MRSA Agents

doi: 10.1021/acsmedchemlett.6b00289

Figure Lengend Snippet: Antibacterial Activity of Compounds 11 , 12 , 19 , 22 , and 24 against Z172, VRE and Several Gram Negative Bacteria

Article Snippet: These results suggested that carbazole-based inhibitors might hit a different target(s) compared to vancomycin as compounds 12 and 19 exerted potent activities against both VRE (ATCC 51299) and a vancomycin-intermediate and daptomycin-nonsusceptible MRSA strain (Z172). table ft1 table-wrap mode="anchored" t5 Table 2 caption a7 minimum inhibitory concentration (μg/mL) compd Z172 a ATCC 51299 (VRE) ATCC 25922 ( E. coli ) ATCC 27853 ( P. aeruginosa ) ATCC 700603 ( K. pneumoniae ) ATCC 19606 ( A. baumannii ) 11 2 2 8–16 >64 >64 16 12 2 1 >64 >64 >64 >64 19 1 1 4 >64 >64 8 22 1 2 >64 >64 >64 >64 24 4 2 >64 >64 >64 >64 vancomycin 4 8–16 N.A.

Techniques: Activity Assay, Bacteria, Concentration Assay

Journal: Communications Biology

Article Title: Synthetic indole derivatives as an antibacterial agent inhibiting respiratory metabolism of multidrug-resistant gram-positive bacteria

doi: 10.1038/s42003-024-06996-8

Figure Lengend Snippet: MIC values of SMJ-2 and SMJ-4 against various strains

Article Snippet: ATCC 51299* (VRE) , 0.25 , 0.25 , 32 , 128 , ≤1 , ≥128.

Techniques: